NAD+ studies have demonstrated improved blood pressure and liver health, as well as improving the body's response to stress, exercise endurance, epigenetic regulation, as well as having anti-aging, energy producing, and anti-inflammatory properties. NAD+ levels naturally decline aging and with chronic disease. A decline in NAD+ levels is closely related to the development of various metabolic disorders, including diabetes and fatty liver disease and leading to an increase in DNA damaging reactive oxygen species. This is a 500 mg dosage. Please allow for 2-4 hours of time for administration.